Spatial organization of transmembrane receptor signalling
نویسندگان
چکیده
منابع مشابه
Spatial organization of transmembrane receptor signalling.
The spatial organization of transmembrane receptors is a critical step in signal transduction and receptor trafficking in cells. Transmembrane receptors engage in lateral homotypic and heterotypic cis-interactions as well as intercellular trans-interactions that result in the formation of signalling foci for the initiation of different signalling networks. Several aspects of ligand-induced rece...
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Since the early days of light microscopy it has been apparent that cells are highly organized and compartmentalized. However, only in recent decades has the molecular basis of this spatial organization and its functional role in cellular signalling events emerged. Furthermore, modern molecular and imaging techniques, together with the intricate combination of cellular and developmental biologic...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2010
ISSN: 0261-4189,1460-2075
DOI: 10.1038/emboj.2010.175